NPJ Precision Oncology (2026)

An antibody-drug conjugate designed through clone and isotype selection restricts the growth of CSPG4-expressing triple-negative breast cancer

Esapa, B., Liu, Y., Chenoweth, A.M., Stoker, K., Łabędź, N., Romero-Clavijo, P., Ilieva, K.M., Trendell, J., Navarro-Llinas, B., Suriawinata, E., Butcher, T., Wang, N., Grandits, M., Palhares, L.C.G.F., McCraw, A., Crescioli, S., Johansson, A., Irshad, S., Grigoriadis, A., Gazinska, P., Tsoka, S., Chudasama, V., Baker, J.R., Tutt, A.N.J., Cheung, A., Thurston, D.E. & Karagiannis, S.N.

10.1038/s41698-026-01341-0
An antibody-drug conjugate designed through clone and isotype selection restricts the growth of CSPG4-expressing triple-negative breast cancer
Nature (2025)

Spatial fibroblast niches define Crohn’s fistulae

McGregor, C., Qin, X., Jagielowicz, M., Gupta, T., Yin, Z., Lentsch, V., Fawkner-Corbett, D., Lai, V. W., Gomez Castro, P., Bridges, E., Lee, C. H., Chuang, H.-W., Deng, L., Aulicino, A., Teague, R., Moradi, S., Park, J. S., Woo, J., Xu, K., Tandon, R., Cianci, N., Bornschein, J., Ho, L.-P., Siejka-Zielinska, P., Christoforidou, Z., Hill, S., Lehmann, J., Kujawa, R., Vargas Gutierrez, P., Cheng, C., Greco, M., Baker, K., Bignell, M., George, B., Fryer, E., Vieth, M., Antanaviciute, A., & Simmons, A.

10.1038/s41586-025-09744-y
Spatial fibroblast niches define Crohn’s fistulae