COMING SOON: LED PX3 Photo-Crosslinking Device

Coming soon! The new LEDPX3 device will be available to order soon. Please contact our customer support team to be added to the waiting list.

LED Photo-Crosslinking Device (LED PX)

For Research Use Only.

AlphaThera’s LED PX3 is a next-generation 365 nm LED UV crosslinker uses non-damaging blacklight (365 nm) to enable the efficient and site-specific labeling of antibodies with all oYo-Link® products.

The LED PX3 uses non-damaging 365 nm blacklight and an advanced LED module to provide precise and uniform UV exposure without the use of mercury lamps. Compared with conventional bulb-based UV systems, the LED PX3 produces less heat while maintaining controlled irradiation performance.

LED PX3 Crosslinking device for antibody labeling with oYo-Link

Intended use:

The LED PX3 is intended for in vitro laboratory research use only.

The device is not intended for:

  • Clinical diagnostic use
  • Human diagnostic procedures
  • Use with clinical samples
  • Operation in moist or humid environments


Note: oYo-Link products are compatible with a wide range of long-wavelength (365 nm) UV photo-crosslinking devices. Suitable alternatives include UVP UVL-56 and UVP CL-1000L. See the list of suitable alternative photo-crosslinking devices here. Please note that no UK-compatible power supply is provided.

LED PX3 Crosslinking device for antibody labeling with oYo-Link
COMING SOON: LED PX3 Photo-Crosslinking Device
COMING SOON: LED PX3 Photo-Crosslinking Device
COMING SOON: LED PX3 Photo-Crosslinking Device

LED PX3 Device Quick User Guide

Download the LED PX3 Quick User Guide for device operation instructions.

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How To: Use the LED PX3 Crosslinking Device

The AlphaThera LED PX3 Device is a next-generation 365 nm LED UV crosslinker designed to enable efficient and site-specific labeling of antibodies with oYo-Link® products. In this short How To video we show you how to use the LED PX3 device.

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Specifications:

Product Specification Sheet

Download the LED PX3 product specification sheet here.
Product Name

LED PX3 Device
Catalog #

AT8003-D
Outside Dimensions

7 inch x 5 1⁄2 inch x 6 ¼ inch (L x W x H)

18 cm x 14 cm x 16 cm (L x W x H)
Voltage (adapter)

100-240V AC 50/60HZ, 1.0A
Fuse (adapter)

36W, 12V, 3A
Bulb Type

LED panel 365 nm
Bulb Base

UV LED LAMP 3WX4
Power

18W, 12V DC, 1.5A
Timer

Set in 5 minute increments up to 120 minutes; Use 120 mins (2 hours) to ensure maximum conjugation efficiency
Intensity

Set in 5% increments up to 100%; Use 75% to keep intensity between 4300 µW/cm2 and 4600 µW/cm2
Fan

Yes
Notes

This LED device is only to be used for in-vitro laboratory research and not to be used for human or clinical samples. Avoid working in moist or humid environments. Always disconnect the main power cord before cleaning the unit or replacing the fuse. WARNING: The blacklight bulbs used in this device emit long wavelength ultraviolet (UV) light (365 nm), which can pose potential health risks including injuries to the skin and eyes. Please exercise caution when the device is running and avoid eye or skin exposure by wearing UV-blocking safety glasses and protective clothing during operation.

Can your UV device be used for photo-crosslinking of other materials under 365 nm UV light?

We haven’t tested the device for other materials and have the concern that the intensity is not sufficient for that purpose. We only use it for antibody-oYo-Link conjugation and the bulb’s energy is only required for 6w-18w, and the intensity is not adjustable.

Does it have built-in safety functions?

The lid of the LED PX3 device contains an integrated safety interlock. Opening the lid automatically disables UV output to prevent accidental exposure.

Is the intensity adjustable?

Yes, the LED PX3 controls UV dosage through a combination of exposure time and lamp intensity, allowing you to optimize photocrosslinking for each reagent protocol.

What is the recommended exposure time?

We receommend 120 minutes (2 hours) for maximum conjugation efficiency.

Are there replacement bulbs?

No, the LED PX3 uses non-damaging 365 nm blacklight and an advanced LED module to provide precise and uniform UV exposure without the use of mercury lamps. Compared with conventional bulb-based UV systems, the LED PX3 produces less heat while maintaining controlled irradiation performance.

What is the UV Intensity Sensor for?

The UV Intensity Sensor is an optional add-on. It allows measurement of the UV intensity inside the irradiation chamber during operation to support QC, reproducibility and protocol validation.

What is the sample capacity of the LED PX3?

The LED PX3 has the capacity for up to 64 samples at a time.

Key features include:

  • 365 nm LED UV illumination
  • High through-put capacity of up to 64 samples
  • Uniform irradiation chamber
  • Adjustable UV intensity to optimize photocrosslinking for each reagent protocol
  • Adjustable exposure time
  • Integrated safety interlock
  • Automatic cooling fan
  • No replacement bulbs – mercury-free, maintenance-free LED module
  • Controls UV dosage through a combination of exposure time and lamp intensity
  • Simple top-mounted control panel
  • Compact laboratory footprint
  • UV-meter add-on supports QC, reproducibility and protocol validation

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